Single Motor Unit Laboratory

SINGLE MOTOR UNIT

We strive to understand how the nervous system controls the motor units within a muscle so as to generate smooth and precise changes in overall muscle force. We also investigate the intrinsic properties of the motor neurons that innervate relevant muscle fiber populations in providing such control.

SINGLE MOTOR UNIT

Hypoxia for SCI rehab

PROJECT TYPE: Spinal Cord Injury

Research Project

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Clinical Trials

Please join our research by considering participation in some of our work.

An Exploration of Acute Intermittent Hypoxia as a tool to Enhance Neural Recovery in Stroke Survivors; a pilot safety study.

This is a Phase I safety study. Our plan consists of dose-escalation exposures with continual assessment of hypoxic conditioning impact in individuals with chronic stroke.

Daily Intermittent Hypoxia and Task-Specific Upper Limb Training in Persons with Chronic Incomplete SCI

This study aims to improve upper extremity function in individuals with chronic incomplete cervical spinal cord injury.

Effect of acute intermittent hypoxia on motor function in individuals with chronic spinal cord injury following ibuprofen pretreatment: A pilot study.

Acute intermittent hypoxia (AIH) enhances lower extremity motor function in humans with chronic incomplete spinal cord injury (SCI). AIH-induced spinal plasticity is inhibited by systemic inflammation in animal models. Since SCI is frequently associated with systemic inflammation in humans, we tested the hypothesis that pretreatment with the anti-inflammatory agent ibuprofen enhances the effects of AIH.