Translational Cell Therapy Lab: Publications

Sex-specific preservation of neuromuscular function and metabolism following systemic transplantation of multipotent adult stem cells in a murine model of progeria.

Thompson SD, Barrett KL, Rugel CL, Redmond R, Rudofski A, Kurian J, Curtin JL, Dayanidhi S, Lavasani M
GeroScience

Systemic transplantation of adult multipotent stem cells prevents articular cartilage degeneration in a mouse model of accelerated ageing.

Thompson SD, Pichika R, Lieber RL, Lavasani M
Immunity & ageing : I & A

Systemic Transplantation of Adult Multipotent Stem Cells

Thompson SD, Pichika R, Lieber RL, Budinger GRS, Lavasani M
Aging and disease

Mesenchymal stem cell-derived extracellular vesicles reduce senescence and extend health span in mouse models of aging.

Dorronsoro A, Santiago FE, Grassi D, Zhang T, Lai RC, McGowan SJ, Angelini L, Lavasani M, Corbo L, Lu A, Brooks RW, Garcia-Contreras M, Stolz DB, Amelio A, Boregowda SV, Fallahi M, Reich A, Ricordi C, Phinney DG, Huard J, Lim SK, Niedernhofer LJ, Robbins PD
Aging cell

Ovarian transcriptome associated with reproductive senescence in the long-living Ames dwarf mice.

Schneider A, Matkovich SJ, Saccon T, Victoria B, Spinel L, Lavasani M, Bartke A, Golusinski P, Masternak MM
Molecular and cellular endocrinology

mTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging.

Takayama K, Kawakami Y, Lavasani M, Mu X, Cummins JH, Yurube T, Kuroda R, Kurosaka M, Fu FH, Robbins PD, Niedernhofer LJ, Huard J
Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Biologic strategies to improve nerve regeneration after peripheral nerve repair.

Fowler JR, Lavasani M, Huard J, Goitz RJ
Journal of Reconstructive Microsurgery

Involvement of ERCC1 in the pathogenesis of osteoarthritis through the modulation of apoptosis and cellular senescence.

Takayama K, Kawakami Y, Lee S, Greco N, Lavasani M, Mifune Y, Cummins JH, Yurube T, Kuroda R, Kurosaka M, Fu FH, Huard J
Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Human muscle-derived stem/progenitor cells promote functional murine peripheral nerve regeneration.

Lavasani M, Thompson SD, Pollett JB, Usas A, Lu A, Stolz DB, Clark KA, Sun B, Péault B, Huard J
The Journal of clinical investigation

The microenvironment-specific transformation of adult stem cells models malignant triton tumors.

Lavasani M, Pollett JB, Usas A, Thompson SD, Pollett AF, Huard J
PloS one

Platelet-rich plasma promotes the proliferation of human muscle derived progenitor cells and maintains their stemness.

Li H, Usas A, Poddar M, Chen CW, Thompson S, Ahani B, Cummins J, Lavasani M, Huard J
PloS one

Muscle-derived stem/progenitor cell dysfunction in Zmpste24-deficient progeroid mice limits muscle regeneration.

Song M, Lavasani M, Thompson SD, Lu A, Ahani B, Huard J
Stem cell research & therapy

Isolation of muscle-derived stem/progenitor cells based on adhesion characteristics to collagen-coated surfaces.

Lavasani M, Lu A, Thompson SD, Robbins PD, Huard J, Niedernhofer LJ
Methods in molecular biology (Clifton, N.J.)

NF-κB negatively impacts the myogenic potential of muscle-derived stem cells.

Lu A, Proto JD, Guo L, Tang Y, Lavasani M, Tilstra JS, Niedernhofer LJ, Wang B, Guttridge DC, Robbins PD, Huard J
Molecular therapy : the journal of the American Society of Gene Therapy

Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model.

Lavasani M, Robinson AR, Lu A, Song M, Feduska JM, Ahani B, Tilstra JS, Feldman CH, Robbins PD, Niedernhofer LJ, Huard J
Nature communications

Terminal differentiation is not a major determinant for the success of stem cell therapy - cross-talk between muscle-derived stem cells and host cells.

Gharaibeh B, Lavasani M, Cummins JH, Huard J
Stem cell research & therapy

Venous graft-derived cells participate in peripheral nerve regeneration.

Lavasani M, Gehrmann S, Gharaibeh B, Clark KA, Kaufmann RA, Péault B, Goitz RJ, Huard J
PloS one

Relationships between transforming growth factor-beta1, myostatin, and decorin: implications for skeletal muscle fibrosis.

Zhu J, Li Y, Shen W, Qiao C, Ambrosio F, Lavasani M, Nozaki M, Branca MF, Huard J
The Journal of biological chemistry

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