Seth Thompson, PhD

Seth Thompson, PhD

Research Scientist I

My Lab

Translational Cell Therapy Lab

Studying the relationship between adult stem/progenitor cell dysfunction and age-related degeneration.

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About Me

Seth Thompson has been involved in biomedical research for over 15 years in the areas of infectious disease, immunology, and regenerative medicine. Seth previously worked at the University of Pittsburgh and came to the Rehabilitation Institute of Chicago to work with Dr. Mitra Lavasani on investigating novel cellular therapeutics for neuronal injuries and degenerative diseases. He completed his PhD at Northwestern University in the Interdepartmental Neuroscience (NUIN) program researching novel systemic treatments to simultaneously rejuvenate multiple neuromusculoskeletal tissues in naturally aged mice. As a Research Scientist in the Translational Cell Therapy Lab, his current research focuses on investigating the application of adult human stem cells and their therapeutic secreted factors to improve neuromuscular function in mouse models of aging. Furthermore, he assesses host and donor mechanisms that support tissue regeneration and behavioral phenotypic changes.

Location

Shirley Ryan AbilityLab

355 East Erie

Chicago, IL 60611

Education & Training

  • Education

    2016 – 2022

    Ph.D., Neuroscience, Northwestern University

    2004 – 2008

    B.Sc., Biology; Biotechnology, James Madison University

  • Fellowship

    2022 – 2024

    Postdoctoral Fellowship, Translational Cell Therapy Lab, Shirley Ryan AbilityLab; Physical Medicine and Rehabilitation, Northwestern University

Recent Publications

Sex-specific preservation of neuromuscular function and metabolism following systemic transplantation of multipotent adult stem cells in a murine model of progeria.
Thompson SD, Barrett KL, Rugel CL, Redmond R, Rudofski A, Kurian J, Curtin JL, Dayanidhi S, Lavasani M
GeroScience
doi: 10.1007/s11357-023-00892-5
Systemic Transplantation of Adult Multipotent Stem Cells Functionally Rejuvenates Aged Articular Cartilage.
Thompson SD, Pichika R, Lieber RL, Budinger GRS, Lavasani M
Aging and disease
doi: 10.14336/AD.2020.1118
Systemic transplantation of adult multipotent stem cells prevents articular cartilage degeneration in a mouse model of accelerated ageing.
Thompson SD, Pichika R, Lieber RL, Lavasani M
Immunity & ageing : I & A
doi: 10.1186/s12979-021-00239-8

Honors & Awards

  • The Sarah Baskin Outstanding Research Award Junior Physicians and Scientists category for best manuscript
    2020

Research Interests

  • Adult Stem Cell Transplantation
  • Aging
  • Peripheral Nerve Regeneration
  • Neurodegeneration
  • Neuropathy