Midwest Regional Spinal Cord Injury Care System (MRSCICS)

Midwest Regional Spinal Cord Injury Care System (MRSCICS) at Shirley Ryan AbilityLab is a leading center for innovative, integrated, interdisciplinary research and care for persons with SCI and is one of the original five NIDILRR-designated Model System Spinal Cord Injury Centers (in partnership with Northwestern University and Northwestern Memorial Hospital).

Midwest Regional Spinal Cord Injury Care System (MRSCICS)

Using a Health Technology Assessment Framework for Evaluating the Utilization and Efficiency of Wearable Exoskeleton for SCI Rehab

PROJECT TYPE: Spinal Cord Injury

Research Project

Evaluating the Utility of Spasticity and Brain-Derived Neurotrophic Factor (BDNF) in Pre-dicting Neurologic and Motor Functional Recovery after SCI

Research Project

Improving Adherence to Exercise Guidelines Using Smartphone-Based Technology and E-coaching: A Proof-of-Concept SMART-Design Study

Research Project

Characterizing the Experience of Spasticity after Spinal Cord Injury

PROJECT TYPE: Spinal Cord Injury, Outcomes

Research Project

Spinal Cord Injury Model Systems Equity and Quality in Assistive Technology (EQuATe) 2.0 Module

PROJECT TYPE: Outcomes

Research Project

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Selected Publications

Multisite Hebbian Plasticity Restores Function in Humans with Spinal Cord Injury

OBJECTIVE: Spinal cord injury (SCI) damages synaptic connections between corticospinal axons and motoneurons of many muscles, resulting in devastating paralysis. We hypothesized that strengthening corticospinal-motoneuronal synapses at multiple spinal cord levels through Hebbian plasticity (i.e., "neurons that fire together, wire together") promotes recovery of leg and arm function. METHODS: Twenty participants with chronic SCI were randomly assigned to receive 20-sessions of Hebbian or sham…

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