Defining Trajectories of Linguistic, Cognitive-Communication and Quality of Life Outcomes in Aphasia
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About this Research Study
Stroke imposes significant burdens on the health and quality of life of survivors and their caregivers and presents a major public health issue in terms of healthcare costs and lost productivity. Aphasia adds to the cost of stroke-related care.
Many stroke survivors with aphasia receive therapy in inpatient rehabilitation facilities. However, aphasia recovery is variable and there is limited evidence on how inpatient rehabilitation and other forms of treatment contribute to the outcomes of patients. This study aims to describe the trajectories of linguistic, cognitive-communicative, and health-related quality of life outcomes following stroke aphasia.
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This study has three objectives
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Establish a prospective cohort of stroke patients with aphasia, and define their typical trajectory of linguistic, cognitive-communicative, and health-related quality of life recovery at admission to and discharge from the inpatient rehabilitation facility, and at 6, 12, and 18 months after stroke.
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Identify factors that are associated with linguistic, cognitive-communicative, and health-related quality of life outcomes from among the following: patient factors including demographic and clinical characteristics related to stroke and aphasia; treatment variables including inpatient and outpatient aphasia therapy characteristics and informal aphasia services; and biomarkers, including genetic and neuroimaging biomarkers.
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Evaluate the stability of the models of linguistic, cognitive-communicative, and health-related quality of life outcomes recovery
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Our Mission
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A sample of 300 newly-admitted stroke patients with aphasia recruited at four Midwestern rehabilitation hospitals will complete measures of linguistic and cognitive-communicative performance and quality of life measures during inpatient rehabilitation and at 6-, 12-, and 18- months after stroke. We will model outcomes as individual and group trajectories, allowing us to develop individual predictions that could inform clinical planning and decision-making for future patients.
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Lab News
Mentioned Page
SRAlab Receives Grant to Study Quality of Life in Stroke Survivors with Aphasia
Inside LookOur Team
Mentioned Profile
Allen Heinemann, PhD
Director, Center for Rehabilitation Outcomes Research Professor, Department of PM&R, Feinberg School of Medicine, NorthwesternBody
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Shirley Ryan AbilityLab |
Role |
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Co-PI |
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Co-PI |
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Genetics |
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Neuroimaging |
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Al Kozlowski |
Co-I |
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Mary Kwasny |
Biostatestitian |
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Linda Lovell |
Research Administrator |
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Elizabeth Salley |
Project Manager |
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Rosalind Hurwitz |
SLP |
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Stacy Chrzastowski |
SLP |
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Tertia Jeppson |
SLP |
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Brooke Boxrud |
Research Assistant |
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Alexian/ AMITA staff |
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Katherine Enzler |
Site Manager |
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MFB Staff |
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Jessica DeGroot |
SLP/Site Manager |
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Marianjoy Staff |
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Michelle Armour |
SLP/Site Manager |
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Clare Goodman |
SLP |